Consider this medication just as prescribed to decrease the potential risk of addiction. Inquire your health care provider or pharmacist for more details.

Do not boost your dose or use this merchandise extra frequently or for more time than prescribed. Your problem will likely not increase any speedier, along with your danger of side effects will maximize.

The following laboratory exams could be influenced in patients who are acquiring therapy with promethazine hydrochloride.

Concomitant administration of promethazine products and solutions with other respiratory depressants has an Affiliation with respiratory depression, and at times Demise, in pediatric individuals.

Animal replica studies have not been performed Along with the drug mix-promethazine and codeine. It is not recognised no matter if this drug combination may cause fetal harm when administered to your Expecting lady or can have an affect on copy potential.

Epinephrine – Due to potential for promethazine to reverse epinephrine’s vasopressor impact, epinephrine really should not be applied to deal with hypotension connected with promethazine overdose.

Promethazine administered to some Expecting woman inside of two months of supply may inhibit platelet aggregation in the new child.

Don't flush drugs down the toilet or pour them into a drain Except if instructed to do so. Adequately discard this product or service when it is actually expired or no longer necessary. Talk to your pharmacist or neighborhood waste disposal company.

Respiratory depression leading to arrest, coma, and Demise has transpired with the use of codeine antitussives in young small children, specifically within the beneath-one particular-12 months infants whose capacity to deactivate the drug just isn't entirely designed.

Promethazine is well absorbed from your gastrointestinal tract. Scientific consequences are clear inside 20 minutes immediately after oral administration and usually past four to six hrs, Even though they may persist providing 12 hrs. Promethazine is metabolized with the liver to a number of compounds; the sulfoxides of promethazine and N-demethylpromethazine are definitely Promethazine codeine syrup the predominant metabolites showing inside the urine.

Clients ought to be encouraged to measure Promethazine with Codeine Oral Option with the accurate measuring product. A home teaspoon just isn't an accurate measuring unit and may lead to overdosage, particularly when a half a teaspoon is measured.

Promethazine hydrochloride and codeine phosphate must be provided to the Expecting female only if clearly wanted.

e., many copies from the gene for cytochrome P450 isoenzyme CYP2D6 or superior morphine concentrations). These kids could possibly be significantly delicate towards the respiratory depressant outcomes of codeine which has been rapidly metabolized to morphine. Codeine is contraindicated for write-up-operative soreness administration in these clients (see WARNINGS – Death Linked to Ultra-Speedy Metabolism of Codeine to Morphine and CONTRAINDICATIONS). The mixture of promethazine hydrochloride and codeine phosphate should be made use of with caution in pediatric clients 6 years and older (see WARNINGS - Use in Pediatric Individuals).

If the two medicines are prescribed alongside one another, your health practitioner may well alter the dose or how often you utilize just one or equally on the medicines.